Handbook of Nanoindentation: With Biological Applications Hardcover - 2010
by Michelle L. Oyen (Editor)
From the jacket flap
Nanoindentation is ideal for the characterization of inhomogeneous biological materials. However, the use of nanoindentation techniques in biological systems is associated with some distinctively different techniques and challenges. For example, engineering materials used in the microelectronics industry (e.g. ceramics and metals) for which the technique was developed, are relatively stiff and exhibit time-independent mechanical responses. Biological materials, on the other hand, exhibit time-dependent behavior, and can span a range of stiffness regimes from moduli of Pa to GPa eight to nine orders of magnitude. As such, there are differences in the selection of instrumentation, tip geometry, and data analysis in comparison with the "black box" nanoindentation techniques as sold by commercial manufacturers. The use of scanning probe equipment (atomic force miscroscopy) is also common for small-scale indentation of soft materials in biology.
The book is broadly divided into two parts. The first part presents the "basic science" of nanoindentation including the background of contact mechanics underlying indentation technique, and the instrumentation used to gather mechanical data. Both the mechanics background and the instrumentation overview provide perspectives that are optimized for biological applications, including discussions on hydrated materials and adaptations for low-stiffness materials. The second part of the book covers the applications of nanoindentation technique in biological materials. Included in the coverage are mineralized and nonmineralized tissues, wood and plant tissues, tissue-engineering substitute materials, cells and membranes, and cutting-edge applicationsat molecular level including the use of functionalized tips to probe specific molecular interactions (e.g. the ligand-receptor binding). The book concludes with a concise summary and an insightful forecast of the future highlighting the current challenges.
Details
- Title Handbook of Nanoindentation: With Biological Applications
- Author Michelle L. Oyen (Editor)
- Binding Hardcover
- Edition Brand new
- Pages 358
- Volumes 1
- Language ENG
- Publisher Jenny Stanford Publishing
- Date 2010-10
- Illustrated Yes
- Features Bibliography, Illustrated, Index, Table of Contents
- ISBN 9789814241892 / 981424189X
- Weight 1.85 lbs (0.84 kg)
- Dimensions 9.8 x 6.8 x 0.9 in (24.89 x 17.27 x 2.29 cm)
- Dewey Decimal Code 620.112
Media reviews
Citations
- Reference and Research Bk News, 08/01/2011, Page 270
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