Lymphoma Hardcover - 2005
by Tim Illidge (Editor); Peter W. Johnson (Editor)
From the rear cover
The tremendous progress made over the last few years in our molecular understanding of lymphocyte biology and lymphoma classification promises to have a major impact on clinical practice. In Lymphoma: Methods and Protocols, leading clinical investigators from world renowned laboratories describe in step-by-step detail the latest molecular techniques being used to better understand, classify, and treat lymphoma. Among the highlights are methods to use immunoglobulin gene rearrangements as markers of clonality, to exploit patterns of somatic mutation in the variable regions to indicate at which stage transformation occurred, and to apply gene arrays to the question of biological heterogeneity in morphologically similar diseases. Research methodologies that are highly likely to become routine practice in the future, such as DNA microarray and immunoglobulin V-gene rearrangements, and measurement of minimal disease, are included. There are also molecular techniques for producing novel therapeutics, such as a DNA vaccine with patient-specific sequences derived from the lymphoma in question. The protocols follow the successful Methods in Molecular Medicine(TM) series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.
Cutting-edge and highly practical, Lymphoma: Methods and Protocols offers oncologists, hematologists, and clinical scientists a diverse collection of readily reproducible techniques for the molecular diagnosis and prognostic evaluation of lymphomas.
Details
- Title Lymphoma
- Author Tim Illidge (Editor); Peter W. Johnson (Editor)
- Binding Hardcover
- Edition U. S. EDITION
- Pages 342
- Volumes 1
- Language ENG
- Publisher Humana
- Date 2005-05-17
- Illustrated Yes
- Features Bibliography, Illustrated, Index
- ISBN 9781588291592 / 1588291596
- Weight 1.57 lbs (0.71 kg)
- Dimensions 9.36 x 6.14 x 0.99 in (23.77 x 15.60 x 2.51 cm)
- Library of Congress subjects Genetic Techniques, Clinical Laboratory Techniques
- Library of Congress Catalog Number 2004026632
- Dewey Decimal Code 616.994
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Lymphoma (Methods in Molecular Medicine, 115)
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LYMPHOMA
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