Skip to content

Model Organisms in Drug Discovery
Stock Photo: Cover May Be Different

Model Organisms in Drug Discovery Hardcover - 2003

by Pamela M. Carroll (Editor); Kevin Fitzgerald (Editor)

From the publisher

Modellorganismen sind sehr hilfreich bei einem systematischen Ansatz zur Klrung einer breiten Palette krankheitsbezogener Fragestellungen.

Aufgrund fortgeschrittener Gentechniken fr Modellorganismen und die Verfgbarkeit ihrer Genomsequenzen, knnen diese Organismen einen gro en Einfluss auf die Wirkstoffentdeckung haben, insbesondere in dem kritischen Bereich der Targetvalidierung krankheitsrelevanter Proteine.

Dieses topaktuelle Buch erlutert die neuesten Fortschritte in den Bereichen Bioinformatik, Proteomik, Genomik sowie Biochemische- und Automationstechnologien, soweit sie sich auf einfache Organismen beziehen, die in der Wirkstoffentdeckung eingesetzt werden.

Fhrende Experten auf diesem Gebiet berichten hier umfassend ber den Bereich der Erforschung von Modellorganismem, die einen gro en Einfluss auf spezifische Therapiebereiche ausgebt hat.

Darber hinaus analysieren sie topaktuelle Anwendungen von Modellsystemen, beschreiben Anwendungen in der Praxis und mgliche Zukunftsperspektiven.

"Model Organisms in Drug Discovery" - eine ntzliche Lektre nicht nur fr Fachleute in der Wirkstoffentdeckung, sondern fr eine Vielzahl von Wissenschaftlern.

First line

A major challenge in the 'post-genomic' world is to rapidly uncover the proteins that may become the high-quality therapeutic targets of the future.

From the rear cover

Fruit flies are "little people with wings" goes the saying in the scientific community, ever since the completion of the Human Genome Project and its revelations about the similarity amongst the genomes of different organisms. It is humbling that most signaling pathways which "define" humans are conserved in Drosophila, the common fruit fly. Feed a fruit fly caffeine and it has trouble falling asleep; feed it antihistamines and it cannot stay awake. A C. elegans worm placed on the antidepressant flouxetine has increased serotonin levels in its tiny brain. Yeast treated with chemotherapeutics stop their cell division. Removal of a single gene from a mouse or zebrafish can cause the animals to develop Alzheimer's disease or heart disease. These organisms are utilized as surrogates to investigate the function and design of complex human biological systems.

Advances in bioinformatics, proteomics, automation technologies and their application to model organism systems now occur on an industrial scale. The integration of model systems into the drug discovery process, the speed of the tools, and the in vivo validation data that these models can provide, will clearly help definition of disease biology and high-quality target validation. Enhanced target selection will lead to the more efficacious and less toxic therapeutic compounds of the future.

This book will be of interest to geneticists, bioinformaticians, pharmacologists, molecular biologists and people working in the pharmaceutical industry, particularly genomics.

Details

  • Title Model Organisms in Drug Discovery
  • Author Pamela M. Carroll (Editor); Kevin Fitzgerald (Editor)
  • Binding Hardcover
  • Edition U.S. Edition
  • Pages 288
  • Volumes 1
  • Language ENG
  • Publisher Wiley, 1
  • Date December 19, 2003
  • Illustrated Yes
  • Features Illustrated, Index, Table of Contents
  • ISBN 9780470848937 / 0470848936
  • Weight 1.45 lbs (0.66 kg)
  • Dimensions 9.9 x 6.78 x 0.86 in (25.15 x 17.22 x 2.18 cm)
  • Library of Congress subjects Pharmacogenomics, Drugs - Research
  • Library of Congress Catalog Number 2003013114
  • Dewey Decimal Code 615.19

About the author

Pamela M. Carroll is the editor of Model Organisms in Drug Discovery, published by Wiley.

Kevin Fitzgerald is the editor of Model Organisms in Drug Discovery, published by Wiley.

More Copies for Sale

Model Organisms in Drug Discovery.

Model Organisms in Drug Discovery.

by Pamela M. Carroll and Kevin Fitzgerald.

  • Used
  • Fine
  • Hardcover
Condition
Used - Fine
Binding
Hardcover
ISBN 10 / ISBN 13
9780470848937 / 0470848936
Quantity Available
1
Seller
Aldeburgh, Suffolk, United Kingdom
Seller rating:
This seller has earned a 5 of 5 Stars rating from Biblio customers.
Item Price
€35.84
€26.29 shipping to USA

Show Details

Description:
Chichester: John Wiley & Sons, 2003. Hardcover Hardcover. Fine. Large octavo. xiv, 288pp. Slight bruising to extremities, otherwise a near fine, unread copy. No jacket as issued.
Item Price
€35.84
€26.29 shipping to USA
Model Organisms In Drug Discovery
Stock Photo: Cover May Be Different

Model Organisms In Drug Discovery

by Carroll

  • New
Condition
New
ISBN 10 / ISBN 13
9780470848937 / 0470848936
Quantity Available
1
Seller
New Delhi, India
Seller rating:
This seller has earned a 5 of 5 Stars rating from Biblio customers.
Item Price
€144.93
€4.72 shipping to USA

Show Details

Description:
New/New. Brand New Original US Edition, Perfect Condition. Printed in English. Excellent Quality, Service and customer satisfaction guaranteed!
Item Price
€144.93
€4.72 shipping to USA
Model Organisms in Drug Discovery
Stock Photo: Cover May Be Different

Model Organisms in Drug Discovery

  • New
  • Hardcover
Condition
New
Binding
Hardcover
ISBN 10 / ISBN 13
9780470848937 / 0470848936
Quantity Available
4
Seller
Woodside, New York, United States
Seller rating:
This seller has earned a 5 of 5 Stars rating from Biblio customers.
Item Price
€167.95
€3.77 shipping to USA

Show Details

Description:
John Wiley & Sons , pp. xiii + 288 . Hardback. New.
Item Price
€167.95
€3.77 shipping to USA
Model Organisms In Drug Discovery (Hb 2003)
Stock Photo: Cover May Be Different

Model Organisms In Drug Discovery (Hb 2003)

by Carroll

  • Used
Condition
New
ISBN 10 / ISBN 13
9780470848937 / 0470848936
Quantity Available
5
Seller
Indianapolis, Indiana, United States
Seller rating:
This seller has earned a 5 of 5 Stars rating from Biblio customers.
Item Price
€190.13
€11.94 shipping to USA

Show Details

Description:
Like New.
Item Price
€190.13
€11.94 shipping to USA
Model Organisms in Drug Discovery
Stock Photo: Cover May Be Different

Model Organisms in Drug Discovery

by Carroll, Pamela M. (Editor)/ FitzGerald, Kevin J. (Editor)

  • New
  • Hardcover
Condition
New
Binding
Hardcover
ISBN 10 / ISBN 13
9780470848937 / 0470848936
Quantity Available
1
Seller
Exeter, Devon, United Kingdom
Seller rating:
This seller has earned a 4 of 5 Stars rating from Biblio customers.
Item Price
€265.42
€11.95 shipping to USA

Show Details

Description:
John Wiley & Sons Inc, 2003. Hardcover. New. 1st edition. 302 pages. 10.00x7.00x1.00 inches.
Item Price
€265.42
€11.95 shipping to USA
Model Organisms In Drug Discovery
Stock Photo: Cover May Be Different

Model Organisms In Drug Discovery

by Carroll & Fitzgerald

  • New
  • Hardcover
Condition
New
Binding
Hardcover
ISBN 10 / ISBN 13
9780470848937 / 0470848936
Quantity Available
1
Seller
New Delhi, India
Seller rating:
This seller has earned a 5 of 5 Stars rating from Biblio customers.
Item Price
€306.72
FREE shipping to USA

Show Details

Description:
United States: John Wiley & Sons, 2003. Hardbound. Brand New. Book Condition:- Brand New. Secured Packaging. Fast DeliveryBookseller Inventory # 9780470848937
Item Price
€306.72
FREE shipping to USA
Model Organisms In Drug Discovery
Stock Photo: Cover May Be Different

Model Organisms In Drug Discovery

by CARROLL

  • New
Condition
New
Edition
USA Edition
ISBN 10 / ISBN 13
9780470848937 / 0470848936
Quantity Available
10
Seller
ROANOKE, Virginia, United States
Seller rating:
This seller has earned a 5 of 5 Stars rating from Biblio customers.
Item Price
€308.53
€3.77 shipping to USA

Show Details

Description:
USA Edition . Brand New. New. Ship within 24hrs. Satisfaction 100% guaranteed. I Ships from multiple Locations I ""Special Note"" We do not Provide Service On APO & PO BOX Box addresses. Delivery with In 7-14 working Day Only. This Books ship from the United Kingdom & USA other locations in India depending on your location and availability.
Item Price
€308.53
€3.77 shipping to USA
Model Organisms In Drug Discovery
Stock Photo: Cover May Be Different

Model Organisms In Drug Discovery

by Carroll

  • New
Condition
New
ISBN 10 / ISBN 13
9780470848937 / 0470848936
Quantity Available
500
Seller
New Delhi, Delhi, India
Seller rating:
This seller has earned a 5 of 5 Stars rating from Biblio customers.
Item Price
€496.49
€14.15 shipping to USA

Show Details

Description:
John Wiley (Original), 2003. New.
Item Price
€496.49
€14.15 shipping to USA
Model Organisms In Drug Discovery
Stock Photo: Cover May Be Different

Model Organisms In Drug Discovery

by Carroll

  • New
Condition
New
ISBN 10 / ISBN 13
9780470848937 / 0470848936
Quantity Available
500
Seller
New Delhi, Delhi, India
Seller rating:
This seller has earned a 5 of 5 Stars rating from Biblio customers.
Item Price
€496.49
€14.15 shipping to USA

Show Details

Description:
John Wiley (Original), 2003. New.
Item Price
€496.49
€14.15 shipping to USA