Label-Free Technologies for Drug Discovery Hardcover - 2011 - 1st Edition
by James Cooper; Lorenz M. Mayr (Editor)
From the rear cover
Over the past two decades the benefits of label-free biosensor analysis have begun to make an impact in the market, and systems are beginning to be used as mainstream research tools in many drug discovery laboratories.
Label-Free Technologies For Drug Discovery summarizes the latest and emerging developments in label-free detection systems, their underlying technology principles and end-user studies that reveal the power and limitations of label-free in all areas of drug discovery.
Label-free technologies discussed include SPR, NMR, high-throughput mass spectrometry, resonant waveguide plate-based screening, transmitted-light imaging, isothermal titration calorimetry, optical and impedance cell-based assays and other biophysical methods. The technologies are discussed in relation to their use as screening technologies, high-content technologies, hit finding and hit validation strategies, mode of action and ADME/T, access to difficult classes, cell-based receptor/ligand interactions particularly orphan receptors, and antibody and small molecule affinity and kinetic analysis.
Label-Free Technologies For Drug Discovery is an essential guide to this emerging class of tools for researchers in drug discovery and development, particularly high-throughput screening and compound profiling teams, medicinal chemists, structural biologists, assay developers, ADME/T specialists, and others interested in biomolecular interaction analysis.
Details
- Title Label-Free Technologies for Drug Discovery
- Author James Cooper; Lorenz M. Mayr (Editor)
- Binding Hardcover
- Edition number 1st
- Edition 1
- Pages 348
- Volumes 1
- Language ENG
- Publisher Wiley, U.S.A
- Date 2011-03-14
- Illustrated Yes
- Features Bibliography, Illustrated, Index
- ISBN 9780470746837 / 0470746831
- Weight 1.4 lbs (0.64 kg)
- Dimensions 9 x 6 x 0.81 in (22.86 x 15.24 x 2.06 cm)
-
Themes
- Aspects (Academic): Science/Technology Aspects
- Library of Congress subjects Drug Design, Drug development
- Library of Congress Catalog Number 2010042191
- Dewey Decimal Code 615.19
Media reviews
Citations
- Reference and Research Bk News, 06/01/2011, Page 276
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