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Target Validation in Drug Discovery
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Target Validation in Drug Discovery Hardcover - 2006 - 1st Edition

by Brian W. Metcalf (Editor); Susan Dillon (Editor)


From the publisher

This work presents a comprehensive contemporary framework for approaching target validation in drug discovery. It begins with a detailed description of new enabling technologies, including aptamers, RNA interference, functional genomics, and proteomics. The next section looks at biologic drug development with in-depth discussion of lessons learned from such well-known cases as Erbitux, Herceptin, and Avastin. Additional targets known as "second generation" drugs, which can be identified when disease pathways are validated by biologics, present new possible small molecule therapeutics and serve as the focus of the final section of the book.

Details

  • Title Target Validation in Drug Discovery
  • Author Brian W. Metcalf (Editor); Susan Dillon (Editor)
  • Binding Hardcover
  • Edition number 1st
  • Edition 1
  • Pages 296
  • Volumes 1
  • Language ENG
  • Publisher Academic Press, St Louis, Missouri, U.S.A.
  • Date 2006-09-01
  • Features Bibliography, Index
  • ISBN 9780123693938 / 0123693934
  • Weight 1.81 lbs (0.82 kg)
  • Dimensions 10.36 x 7.42 x 0.94 in (26.31 x 18.85 x 2.39 cm)
  • Library of Congress subjects Drug Design, Drug development
  • Library of Congress Catalog Number 2006049868
  • Dewey Decimal Code 615.19
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Target Validation in Drug Discovery
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Target Validation in Drug Discovery

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Hardback. New. Presents a comprehensive framework for approaching target validation in drug discovery. This work begins with a description of enabling technologies, including aptamers, RNA interference, and proteomics. It, then, looks at biologic drug development with discussion of lessons learned from such well-known cases as Erbitux, Herceptin, and Avastin.
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Target Validation In Drug Discovery
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Target Validation In Drug Discovery

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Target Validation in Drug Discovery
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Target Validation in Drug Discovery

by Metcalf, Brian W. [Editor]; Dillon, Susan [Editor];

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